ME-344
CAS No. : 1374524-68-1
| Size | Price | Stock |
|---|---|---|
| 5mg | $290 | In-stock |
| 10mg | $450 | In-stock |
| 25mg | $870 | In-stock |
| 50mg | $1480 | In-stock |
| 100mg | $2500 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-112749 |
| M.Wt: | 348.39 |
| Formula: | C22H20O4 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
ME-344 is a mitochondrial Heme oxygenase 1 (HO-1) inhibitor. ME-344 specifically binds and alters HO-1 structure, and increases HO-1 translocation from the rough endoplasmic reticulum to mitochondria, but only in drug-sensitive cells (such as H460 and SHP-77 cells). ME-344 decreases mitochondrial ATP production and induces ROS, with subsequent disruption of redox homeostasis and mitochondrial function. ME-344 has significant antitumor activity, and can be used for cancers like breast cancer research[1].
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