Nω-Propyl-L-arginine


CAS No. : 137361-05-8

(Synonyms: N-omega-Propyl-L-arginine)

137361-05-8
Price and Availability of CAS No. : 137361-05-8
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Cat. No. : HY-102062
M.Wt: 216.28
Formula: C9H20N4O2
Purity: >98 %
Solubility: H2O : ≥ 100 mg/mL
Introduction of 137361-05-8 :

Nω-Propyl-L-arginine (N-omega-Propyl-L-arginine) is a potent, competitive, and highly selective inhibitor of neuronal nitric oxide synthase (nNOS), with a Ki of 57 nM. Nω-Propyl-L-arginine displays a 149-fold selectivity for nNOS over endothelial NOS (eNOS)[1][2]. In Vivo: Nω-Propyl-L-arginine (N-omega-Propyl-L-arginine) (20 mg/kg; i.p.) blocks both phencyclidine-induced disruption of prepulse inhibition and phencyclidine-induced stimulation of locomotor activity[2].

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