LY215840
CAS No. : 137328-52-0
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| Cat. No. : | HY-103148 |
| M.Wt: | 395.54 |
| Formula: | C24H33N3O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
LY215840, a 5-HT7 receptor ligand and a 5-HT2 receptor antagonist, blocks serotonin-induced relaxation in canine coronary artery[1][2].
In Vitro:LY215840 (1 μM) markedly potentiated contraction to 5-carboxamidotryptamine, the most potent coronary relaxant agonist and the agonist with the highest 5-HT7 receptor affinity[1].
LY215840 (3 x 10-10 to 10-8 M) blocks 5-HT2 receptors mediating contraction to 5-HT in vitro[2].
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