Boc-Glu(OtBu)-OH


CAS No. : 13726-84-6

13726-84-6
Price and Availability of CAS No. : 13726-84-6
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Cat. No. : HY-W009229
M.Wt: 303.35
Formula: C14H25NO6
Purity: >98 %
Solubility: DMSO : 200 mg/mL (ultrasonic)
Introduction of 13726-84-6 :

Boc-Glu (OtBu)-OH is a glutamic acid-derived protected amino acid with its N-terminal amino group protected by tert-butyloxycarbonyl (Boc) and side-chain carboxyl group protected by tert-butyl ester (OtBu), serving as an orthogonally protected building block for polypeptide synthesis. Boc-Glu (OtBu)-OH is applicable to research on the synthesis of peptide compounds[1]. In Vitro:Boc-Glu(OtBu)-OH (0°C to room temperature, 30 min) readily undergoes intramolecular cyclization to form tert-butyl pyroglutamate upon deprotection of Boc with 4 M HCl/dioxane[1].

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