Voriconazole
CAS No. : 137234-62-9
(Synonyms: UK-109496)
| Size | Price | Stock |
|---|---|---|
| 5mg | $25 | In-stock |
| 10mg | $40 | In-stock |
| 25mg | $70 | In-stock |
| 50mg | $106 | In-stock |
| 100mg | $138 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-76200 |
| M.Wt: | 349.31 |
| Formula: | C16H14F3N5O |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 50 mg/mL;H2O : 0.17 mg/mL (ultrasonic) |
Voriconazole (UK-109496) is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes. Voriconazole can penetrate the blood brain barrier (BBB)[1][2][3].
In Vitro: Voriconazole has great activity against S. apiospermum and C. neoformans with the MICs of 0.5 μg/mL and 0.125-0.25 μg/mL, respectively[1].
Voriconazole inhibits the cytochrome P450 (CYP)-dependent enzyme 14-alpha-sterol demethylase, thereby disrupting the cell membrane and halting fungal growth[2].
In Vivo: Voriconazole (5-20 mg/kg; p.o. for 21 days) prolongs survival in a dose-dependent fashion. Voriconazole (40 mg/kg/day) decreases the fungal burden in the lungs[3].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- Voriconazole
- Cat. No.:
- HY-76200
- Quantity:
Your information is safe with us.