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|---|---|---|
| 100 mg | Get quote | |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-100295 |
| M.Wt: | 202.21 |
| Formula: | C8H14N2O4 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
(4-Acetamidocyclohexyl) nitrate (BM121307) is a guanylate cyclase activator. In Vivo: The elimination of BM121307 and its metabolites via urine and feces amount to 76.5% after oral application, and to 80.7% of the applied dose after intravenous application. The major amount of radioactivity is eliminated via urine (69.4% and 73.6% of the dose, respectively), whereas the fecal elimination is found to be negligible. Investigations of the urinary samples show that the drug is metabolized to a high percentage trans-N-(4-Hydroxycyclohexyl) acetamide is the main metabolite; 73% of the radioactive compounds (after p.o.-administration and 69% after intravenous application could be identified as the alcohol of BM121307; the amounts of the drug totaled 9% and 13%, respectively[1].
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