Orazipone
CAS No. : 137109-78-5
(Synonyms: OR 1384)
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| Cat. No. : | HY-106981 |
| M.Wt: | 266.31 |
| Formula: | C13H14O4S |
| Purity: | >98 % |
| Solubility: |
Orazipone (OR 1384) is a small molecule immunomodulator with strong anti-inflammatory properties. Orazipone exerts its immunomodulatory effect by forming reversible thiol complexes, which bind to intracellular signaling proteins and the thiol groups of glutathione. Orazipone exhibits potent anti-eosinophilic activity by inducing apoptosis. Orazipone inhibits activation of inflammatory transcription factors NF-kB and STAT 1 and decreases inducible iNOS expression and NO production in response to inflammatory stimuli. Orazipone reduces NADPH oxidase activity and thereby decreases ROS production. Orazipone has a protective effect in intestinal radiation injury[1][2][3].
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