Amprolium (hydrochloride)


CAS No. : 137-88-2

137-88-2
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Cat. No. : HY-B0937A
M.Wt: 315.24
Formula: C14H20Cl2N4
Purity: >98 %
Solubility: H2O : ≥ 200 mg/mL
Introduction of 137-88-2 :

Amprolium hydrochloride is an anti-parasitic drug that's kind of taken orally, and it acts as an antagonist to thiamine in intestinal absorption[1][2][3][4]. In Vivo:Amprolium hydrochloride (1 g/L, oral, daily, for 7 days) can be used as a preventive measure in rabbits in combination with other anti-coccidial drugs[1].
Amprolium hydrochloride (8 mg-2 g, taken orally or injected subcutaneously, daily, for 4-34 days) exerts an antagonistic effect with thiamine primarily at the level of the intestinal epithelial cells, impacting thiamine absorption. Once administered directly bypassing the gut, it does not significantly affect thiamine's entry into other tissue cells[2].

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