CP-99994
CAS No. : 136982-36-0
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| Cat. No. : | HY-12144 |
| M.Wt: | 296.41 |
| Formula: | C19H24N2O |
| Purity: | >98 % |
| Solubility: |
CP-99994 is a Tachykinin neurokinin 1 (NK-1) receptor antagonist with a Ki of 0.25 nM. CP-99994 prevents colorectal sensitization in the context of visceral hypersensitivity. CP-99994 reduces colorectal hypersensitivity induced by acetic acid injections in a model of bladder-colon cross-sensitization. CP-99994 hydrochloride attenuates the neuroglial interactions and MAPK-p38 phosphorylation associated with visceral hypersensitivity[1].
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