RP 70676
CAS No. : 136609-26-2
| Size | Price | Stock |
|---|---|---|
| 5mg | $165 | In-stock |
| 10mg | $250 | In-stock |
| 25mg | $450 | In-stock |
| 50mg | $635 | In-stock |
| 100mg | $886 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-101576 |
| M.Wt: | 416.58 |
| Formula: | C25H28N4S |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic) |
RP 70676 is a potent inhibitor of ACAT, with IC50 of 25 and 44 nM for rat and rabbit ACAT. IC50 & Target: IC50: 25 nM (Rat ACAT), 44 nM (Rabbit ACAT)[1] In Vitro: RP 70676 is a potent inhibitor of rabbit arterial ACAT (IC50 = 40 nM) and has been shown to be an effective inhibitor of ACAT derived from a number of tissues and species including man. The IC50 values range from 21 nM for hamster liver ACAT to 108 nM for enzyme from the intestine of cholesterol fed rabbits; in human hepatic tissues the mean IC50 is 44 nM. In whole cell P388D, murine macrophages the compound has an IC50 of 540 nM. In Vivo: RP 70676 (10 mg/kg, p.o.) is well absorbed with plasma levels in NZW rabbits[1].
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- RP 70676
- Cat. No.:
- HY-101576
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