BMY 42393
CAS No. : 136451-58-6
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| Cat. No. : | HY-120309 |
| M.Wt: | 399.44 |
| Formula: | C25H21NO4 |
| Purity: | >98 % |
| Solubility: |
BMY 42393 is an orally active prostacyclin agonist which suppresses monocyte-macrophage atherogenic activity and cytokine production. BMY 42393 can be used for atherosclerosis research[1].
In Vivo:BMY 42393 (30 mg/kg/d, diet, 10 weeks) inhibits mononuclear cell adhesion by 35%, decreases foam cells per square millimeter by 44%, reduces foam cell size by 26%, reduces fatty streak area by 40%, and decreases intimal oil red O staining by 39% in hamsters received a mild atherogenic diet[1].
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