(Rac)-CCT 250863
CAS No. : 1364269-06-6
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|---|---|---|
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| Cat. No. : | HY-117884 |
| M.Wt: | 490.54 |
| Formula: | C24H25F3N4O2S |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic;warming) |
(Rac)-CCT 250863 (compound rac-21) is a selective and reversible NEK 2 inhibitor with an IC50 of 0.073 µM. (Rac)-CCT 250863 shows good effects of inducing cell cycle arrest and also can antiproliferative in cells (Pomalidomide sensitive/resistant). (Rac)-CCT 250863 induces apoptosis when combines with Pomalidomide[1][2]. IC50 & Target: IC50: 0.073 µM (NEK 2), 8.0 μΜ (H929), 7.1 μΜ (AMOl), 8.7 μΜ (K12PE)[1][2].
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