CID-50930756
CAS No. : 1363454-18-5
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| Cat. No. : | HY-117802 |
| M.Wt: | 558.65 |
| Formula: | C27H18N4O4S3 |
| Purity: | >98 % |
| Solubility: |
CID-50930756 is an HCV NS3 helicase inhibitor with an IC50 of 22 μM.CID-50930756 inhibits HCV NS3 helicase-catalyzed nucleic acid unwinding.CID-50930756 inhibits HCV replication in hepatoma cells harboring a stably transfected subgenomic HCV replicon.CID-50930756 does not exhibit toxicity to hepatoma cells at 10 μM.CID-50930756 shows weak DNA-binding activity, displacing less than 20% of SYBR Green I from DNA at 100 μM.CID-50930756 can be used for the research of hepatitis c[1].
In Vitro:CID-50930756 (Compound 31) (100 μM) exhibits weak DNA-binding activity, displacing 15% of SYBR Green I bound to DNA at a concentration of 100 μM[1].
CID-50930756 (10 μM; 72 h) inhibits the replication of HCV genotype 1b subgenomic replicons in Huh7.5 cells, with an inhibition rate of 51% after treatment with 10 μM for 72 h, and no cytotoxicity is observed[1].
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