Tiotropium (Bromide)
CAS No. : 136310-93-5
(Synonyms: BA679 BR)
| Size | Price | Stock |
|---|---|---|
| 5mg | $35 | In-stock |
| 10mg | $55 | In-stock |
| 50mg | $99 | In-stock |
| 100mg | $143 | In-stock |
| 500mg | $495 | In-stock |
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| 5 g | Get quote | |
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| Cat. No. : | HY-17360 |
| M.Wt: | 472.42 |
| Formula: | C19H22BrNO4S2 |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic);H2O : 25 mg/mL (ultrasonic) |
Tiotropium bromide (BA-679 BR) is a long-acting anticholinergic bronchodilator. Tiotropium bromide blocks the action of acetylcholine at muscarinic M1, M2, and M3 receptors, prevents bronchoconstriction, and dilates bronchial airways. Tiotropium bromide is applicable to research related to chronic obstructive pulmonary disease and asthma[1][2].
IC50 & Target:mAChR
In Vitro:Tiotropium bromide (0-100 nM) preferentially binds to M1 and M3 muscarinic receptors in isolated human lung, tracheal alveolar walls and submucosal glands[2].
Tiotropium bromide potently inhibits electric field stimulation-induced contraction of isolated human bronchi, with an IC50 of 0.24 nM[2].
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