| Size | Price | Stock |
|---|---|---|
| 1mg | $180 | Get quote |
| 5mg | $450 | Get quote |
| 10 mg | Get quote | |
| 50 mg | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-117652 |
| M.Wt: | 234.29 |
| Formula: | C14H18O3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Lobetyol is a natural compound that can be isolated from Lobelia chinensis. Lobetyol induces apoptosis and cell cycle arrest in MKN45 cells. Lobetyol shows anti-virus, anti-inflammation and anti-tumor activity[1][2]. Lobetyol is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
In Vitro:Lobetyol (0-100 μg/mL, 0-48 h) leads to a dose-and time-dependent proliferation inhibition in MKN45 cells[1].
Lobetyol (0-100 μg/mL, 48 h) induces apoptosis and cell cycle arrest in a time- and dose-dependent manner in MKN45 cells[1].
Lobetyol (0-100 μg/mL, 48 h) increases the expression level of Bax, P53, and decreased the expression level of Bcl-2[1].
In Vivo:Lobetyol (0-10 mg/kg, Once per 3 days) suppresses tumor growth in MKN45 nude models[1].
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