MRT-83 (hydrochloride)
CAS No. : 1359944-60-7
| Size | Price | Stock |
|---|---|---|
| 5mg | $120 | In-stock |
| 10mg | $190 | In-stock |
| 25mg | $390 | In-stock |
| 50mg | $670 | In-stock |
| 100mg | $1150 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-18287A |
| M.Wt: | 575.05 |
| Formula: | C31H31ClN4O5 |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic) |
MRT-83 (hydrochloride) is the potent antagonist of Smoothened (Smo) receptor. MRT-83 (hydrochloride) inhibits the Hedgehog (Hh) signaling pathway and BODIPY-cyclopamine binding to human Smo. MRT-83 (hydrochloride) has the potential for researching cancer disease[1]. IC50 & Target: Smo[1] In Vitro: MRT-83 (hydrochloride) (compound 86) has IC50s of 15 and 11 nM respectively in Shh-light2 and C3H10T1/2 cells in the biological activity assay[1].
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