RP 67580


CAS No. : 135911-02-3

135911-02-3
Price and Availability of CAS No. : 135911-02-3
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5mg $200 In-stock
10mg $300 In-stock
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Cat. No. : HY-108483
M.Wt: 438.56
Formula: C29H30N2O2
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 135911-02-3 :

RP 67580 is a non-peptide antagonist of substance P (SP), competitively inhibits the binding of [3H]SP to neurokinin receptor 1 (NK1 receptor) in rat brain membranes with a Ki value of 4.16 nM. RP 67580 is a specific antagonist of NK1 receptors and can be used in the research of pain and neurogenic inflammation[1]. In Vivo:RP 67580 (0.03-1 mg/kg; i.v.; single dose) significantly inhibits neurogenic inflammation.

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