TP-024
CAS No. : 1358575-02-6
(Synonyms: FTBMT)
| Size | Price | Stock |
|---|---|---|
| 5mg | $60 | In-stock |
| 10mg | $115 | In-stock |
| 25mg | $266 | In-stock |
| 50mg | $408 | In-stock |
| 100mg | $612 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-101787 |
| M.Wt: | 392.35 |
| Formula: | C19H16F4N4O |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
TP-024 (FTBMT) is a selective GPR52 agonist with an EC50 of 75 nM[1]. TP-024 has antipsychotic and procognitive properties[2]. IC50 & Target:IC50: 75 nM (GPR52)[1] In Vitro:TP-024 (FTBMT) (0.1-10 μM) increases intracellular cAMP levels in CHO cells expressing human, mouse, or rat GPR52, with pEC50s of 7.03, 6.85, and 6.87, respectively[2]. In Vivo:TP-024 (FTBMT) (30 mg/kg, 90 minutes) exhibits antipsychotic-like activity without causing catalepsy in mice[2].
TP-024 (3 or 10 mg/kg, 48 hours) improves recognition and spatial working memory in rats[2].
TP-024 (3, 10, 30 mg/kg, 2 hours) stimulates neuronal activity in brain regions related to cognition[2].
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