Belizatinib


CAS No. : 1357920-84-3

(Synonyms: TSR-011)

1357920-84-3
Price and Availability of CAS No. : 1357920-84-3
Size Price Stock
2mg $66 In-stock
5mg $110 In-stock
10mg $176 In-stock
25mg $352 In-stock
50mg $495 In-stock
100mg $671 In-stock
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Cat. No. : HY-17603
M.Wt: 577.73
Formula: C33H44FN5O3
Purity: >98 %
Solubility: DMSO : ≥ 300 mg/mL
Introduction of 1357920-84-3 :

Belizatinib (TSR-011) is an orally active, potent inhibitor of ALK and TRKA, TRKB, and TRKC, with IC50 of 0.7 nM for wild-type recombinant ALK kinase. IC50 & Target:IC50: 0.7 nM (ALK)[1] In Vitro:Belizatinib (TSR-011) has antitumour activity. In Vivo:Belizatinib (TSR-011) exerts sustained potent inhibition of ALK-dependent tumour growth in mouse models[1].

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