Vafidemstat


CAS No. : 1357362-02-7

(Synonyms: ORY-2001)

1357362-02-7
Price and Availability of CAS No. : 1357362-02-7
Size Price Stock
5mg $195 In-stock
10mg $304 In-stock
25mg $495 In-stock
50mg $690 In-stock
100mg $970 In-stock
250mg $1460 In-stock
500mg $2100 In-stock
1g $2950 In-stock
5 g Get quote
10 g Get quote
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Cat. No. : HY-112623
M.Wt: 336.39
Formula: C19H20N4O2
Purity: >98 %
Solubility: DMSO : 50 mg/mL (ultrasonic)
Introduction of 1357362-02-7 :

Vafidemstat (ORY-2001) is an oral, brain penetrant, dual lysine-specific histone demethylase (LSD1)/MAO-B inhibitor[1]. IC50 & Target: LSD1/MAO-B[1] In Vitro: Vafidemstat (ORY-2001), a dual LSD1/MAO-B inhibitor, is a novel epigenetic agent for the treatment of neurodegenerative diseases. LSD1 is a protein that participates in transcription regulation complexes; its modulation can be used to tweak transcriptional imbalances in neurodegenerative disease and redress neuroinflammation and cognitive deficit[1]. Vafidemstat (ORY-2001) can be used in the treatment of Alzheimer's disease[2].

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