c-Met inhibitor 1


CAS No. : 1357072-61-7

1357072-61-7
Price and Availability of CAS No. : 1357072-61-7
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5mg $82 In-stock
10mg $124 In-stock
25mg $248 In-stock
50mg $373 In-stock
100mg $560 In-stock
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Cat. No. : HY-15735
M.Wt: 362.41
Formula: C17H14N8S
Purity: >98 %
Solubility: DMSO : 20 mg/mL (ultrasonic)
Introduction of 1357072-61-7 :

c-Met inhibitor 1 is an orally active c-Met inhibitor. c-Met inhibitor 1 can inhibit c-Met phosphorylation with an IC50 of 0.010 μM. c-Met inhibitor 1 has antitumor activity and can be used for the research of tumors such as gastric cancer, pancreatic cancer and malignant glioma[1]. In Vivo:c-Met inhibitor 1 (Example 1) (2-32 mg/kg; oral gavage; twice daily; 28 days) shows antitumor activity in various nude mouse xenograft tumor models[1].

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