HG-14-10-04
CAS No. : 1356962-34-9
| Size | Price | Stock |
|---|---|---|
| 5mg | $125 | In-stock |
| 10mg | $200 | In-stock |
| 25mg | $300 | In-stock |
| 50mg | $390 | In-stock |
| 100mg | $550 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-15801 |
| M.Wt: | 532.08 |
| Formula: | C29H34ClN7O |
| Purity: | >98 % |
| Solubility: | DMSO : 20 mg/mL (ultrasonic) |
HG-14-10-04 is a potent ALK and mutant EGFR inhibitor with IC50s of 20 nM, 15.6 nM, 22.6 nM and 124.5 nM for ALK, EGFRLR/TM, EGFR19del/TM/CS and EGFRLR/TM/CS, respectively. HG-14-10-04 can be used to research anticancer[1][2].
In Vitro: HG-14-10-04 (example 10) has inhibitory activity against ALK kinase with an IC50 of 20 nM[1].
HG-14-10-04 (compound 17b) exhibits kinase inhibitory activity against EGFRLR/TM, EGFR19del/TM/CS and EGFRLR/TM/CS with IC50s of 15.6 nM, 22.6 nM and 124.5 nM, respectively[2].
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- HY-15801
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