GZ-793A
CAS No. : 1356447-90-9
| Size | Price | Stock |
|---|---|---|
| 1mg | $160 | In-stock |
| 5mg | $350 | In-stock |
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| 50 mg | Get quote | |
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| Cat. No. : | HY-117883 |
| M.Wt: | 464.04 |
| Formula: | C26H38ClNO4 |
| Purity: | >98 % |
| Solubility: | H2O : 3 mg/mL (ultrasonic;warming) |
GZ-793A is an orally active and selective vesicular monoamine transporter-2 (VMAT2) inhibitor, with an Ki of 0.029 µM. GZ-793A inhibits the neurochemical effects of methamphetamine (METH)-induced dopamine release. GZ-793A can be used for research of METH addiction[1][2][3].
IC50 & Target: Ki: 0.029 µM (VMAT2)[1].
In Vivo: GZ-793A (30, 60, 120 or 240 mg/kg; p.o.; once) decreases the number of METH infusions self-administered across each time interval evaluats in a dose-dependent manner[1].
GZ-793A (1-100 µM; 90 min) inhibits METH (5 µM)-evoked fractional dopamine releases[2].
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