T-3364366


CAS No. : 1356354-09-0

1356354-09-0
Price and Availability of CAS No. : 1356354-09-0
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10mg $180 In-stock
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Cat. No. : HY-124346
M.Wt: 443.46
Formula: C18H16F3N3O3S2
Purity: >98 %
Solubility: DMSO : 125 mg/mL (ultrasonic)
Introduction of 1356354-09-0 :

T-3364366 is a reversible, slow-binding, thienopyrimidinone delta-5 desaturase (D5D) inhibitor with IC50s of 1.9 nM and 2.1 nM in HepG2 and RLN-10 cells, respectively. T-3364366 exhibits potent D5D (IC500=19 nM) inhibitory activity and excellent selectivity away from delta-6 desaturase (D6D, IC50=6200 nM) and delta-9 desaturase (stearoyl-CoA desaturase, SCD,50 >10000 nM) in the enzymatic activity assay[1].

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