Panulisib
CAS No. : 1356033-60-7
(Synonyms: P7170; AK151761)
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| Cat. No. : | HY-16769 |
| M.Wt: | 527.50 |
| Formula: | C27H20F3N9 |
| Purity: | >98 % |
| Solubility: |
Panulisib (P7170; AK151761) is an orally active inhibitor of PI3K (IC50 = 2.2 nM) and mTOR (IC50 = 4.4 nM). Panulisib inhibits ALK1 and DNA-PK, two enzymes that respectively participate in angiogenesis and DNA repair, with IC50 values of 47 nM and 1.5 nM respectively. Panulisib inhibits cell proliferation and apoptosis. Panulisib can be used for research on breast cancer and non-small cell lung cancer[1][2][3].
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