AWD 140-190
CAS No. : 135548-66-2
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| Cat. No. : | HY-19237 |
| M.Wt: | 365.22 |
| Formula: | C16H17BrN2O3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
AWD 140-190 is a highly effective anticonvulsant agent. AWD 140-190 has shown to block neuronal sodium channels. IC50 & Target: Sodium channels[1] In Vitro: AWD 140–190 acted as a sodium channel blocker in neuronal cells[1]. In Vivo: mice in a range of anticonvulsant tests. AWD 140-190 is active against electrically-induced seizures (ED50 rat p.o.=2.47 mg/kg), in a genetic animal model the DBA/2 mouse, and in corneally kindled rats[2].
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