Mutant IDH1-IN-1


CAS No. : 1355326-21-4

1355326-21-4
Price and Availability of CAS No. : 1355326-21-4
Size Price Stock
5mg $190 In-stock
10mg $290 In-stock
25mg $600 In-stock
50mg $986 In-stock
100mg $1590 In-stock
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Cat. No. : HY-12475
M.Wt: 498.59
Formula: C30H31FN4O2
Purity: >98 %
Solubility: DMSO : ≥ 45 mg/mL
Introduction of 1355326-21-4 :

Mutant IDH1-IN-1 is a mutant-selective IDH1 inhibitor with with IC50s of 4, 42, 80 and 143 nM against mutant IDH1 R132C/R132C, IDH1 R132H/R132H, IDH1 R132H/WT and wild type IDH1, respectively. IC50 & Target:IC50: 4 nM (IDH1 R132C/R132C), 42 nM (IDH1 R132H/R132H), 80 nM (IDH1 R132H/WT), 143 nM (IDH1 wild type)[1]

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