| Size | Price | Stock |
|---|---|---|
| 1mg | $75 | In-stock |
| 5mg | $180 | In-stock |
| 10mg | $280 | In-stock |
| 25mg | $600 | In-stock |
| 50mg | $960 | In-stock |
| 100 mg | Get quote | |
| 200 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
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Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-107749 |
| M.Wt: | 488.58 |
| Formula: | C27H32N6O3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
ML 190 is a selective κ opioid receptor (KOR) antagonist with an IC50 of 120 nM and an EC50 of 129 nM, respectively[1].
IC50 & Target: IC50: 120 nM (KOR)[1]
EC50: 129 nM (KOR)[1]
In Vitro: ML 190 exhibits plasma protein binding of 93.96% (1 μM), 88.54% (10 μM) in human and 88.46% (1 μM), 80.07% (10 μM) in mouse, respectively; plasma remaining percents of 100% at 3 hours in both human and mouse; hepatic microsome remaining percents of 22.13% and 7.34% at 1 hour in human and mouse, respectively; and hepatic toxicity LC50 over 50 μM[1].
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