ML 190


CAS No. : 1355244-02-8

1355244-02-8
Price and Availability of CAS No. : 1355244-02-8
Size Price Stock
1mg $75 In-stock
5mg $180 In-stock
10mg $280 In-stock
25mg $600 In-stock
50mg $960 In-stock
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Cat. No. : HY-107749
M.Wt: 488.58
Formula: C27H32N6O3
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 1355244-02-8 :

ML 190 is a selective κ opioid receptor (KOR) antagonist with an IC50 of 120 nM and an EC50 of 129 nM, respectively[1]. IC50 & Target: IC50: 120 nM (KOR)[1]
EC50: 129 nM (KOR)[1] In Vitro: ML 190 exhibits plasma protein binding of 93.96% (1 μM), 88.54% (10 μM) in human and 88.46% (1 μM), 80.07% (10 μM) in mouse, respectively; plasma remaining percents of 100% at 3 hours in both human and mouse; hepatic microsome remaining percents of 22.13% and 7.34% at 1 hour in human and mouse, respectively; and hepatic toxicity LC50 over 50 μM[1].

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