RO5527239
CAS No. : 1354812-99-9
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| Cat. No. : | HY-116453 |
| M.Wt: | 457.56 |
| Formula: | C28H31N3O3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
RO5527239 is an orally active TGR5 agonist, that induces a stimulatory response from intestinal L cells and specificially secrets the endogenous hormone GLP-2[1]. In Vivo:RO5527239 (30 mg/kg, p.o. for 10 days) stimulates the TGR5 receptor, upregulates L cells and L cells hormone GLP-2, triggers a GLP-2-dependent intestinal adaption in C57BL/6N mice[1].
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