PF-05020182
CAS No. : 1354712-92-7
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| Cat. No. : | HY-108327 |
| M.Wt: | 366.46 |
| Formula: | C18H30N4O4 |
| Purity: | >98 % |
| Solubility: |
PF-05020182 is an orally active opener for Kv7 channel, that activates human Kv7.2/7.3, Kv7.4 and Kv7.3/7.5 with EC50 of 334, 625 and 588 nM, respectively. PF-05020182 exhibits anticonvulsant activity in rats corneal electric shock-induced tonic seizure (MES) models. PF-05020182 is blood-brain barrier (BBB) penetrable[1].
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