Araliadiol
CAS No. : 1354638-93-9
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| Cat. No. : | HY-N2887 |
| M.Wt: | 232.32 |
| Formula: | C15H20O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Araliadiol is a polyacetylenic compound isolated from the leaves of Aralia cordata Thunb. Araliadiol inhibits MCF-7 cells growth with an IC50 value of 6.41 µg/mL[1].
IC50 & Target:IC50: 6.41 µg/mL (MCF-7 cells growth)[1]
In Vitro: Araliadiol (20-80 µM; 0-48 hours; MCF-7 cells) treatment inhibits cell cycle progression of MCF-7 at the G1-S transition[1].
Araliadiol (20-80 µM; 0-48 hours; MCF-7 cells) treatment inhibits phosphorylation of retinoblastoma protein (Rb) in MCF-7 cells, accompanies by a decrease in the levels of cyclin D3 and cdk4 and an increase in the expression of p21 (WAF-1/Cip1)[1].
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