Coluracetam
CAS No. : 135463-81-9
(Synonyms: MKC-231)
| Size | Price | Stock |
|---|---|---|
| 5mg | $25 | In-stock |
| 10mg | $40 | In-stock |
| 50mg | $80 | In-stock |
| 100mg | $90 | In-stock |
| 500mg | $215 | In-stock |
| 1g | $320 | In-stock |
| 5 g | Get quote | |
| 10 g | Get quote | |
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| Cat. No. : | HY-17553 |
| M.Wt: | 341.40 |
| Formula: | C19H23N3O3 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 20 mg/mL;H2O : 0.4 mg/mL (ultrasonic;warming) |
Coluracetam (MKC-231) is an orally taken choline uptake enhancer. Coluracetam can improve the reduced acetylcholine levels in the hippocampus of rats and mice, enhancing learning difficulties, memory deficits, and cognitive impairments. Coluracetam induces a lower degree of hepatic venous hyperglycemia[1][2][3].
In Vivo:Coluracetam (0.3-3 mg/kg, oral, once a day for 11 days) improves the memory deficits and hippocampal acetylcholine depletion in mice induced by AF64A[1].
Coluracetam (1-3 mg/kg, oral, once a day for 8 days) improves cognitive and learning impairments in rats[2].
Coluracetam (5×10-8 and 5×10-7 mol, ventricular injection, single dose) slightly increases hepatic venous glucose levels[3].
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