KH-CB19
CAS No. : 1354037-26-5
| Size | Price | Stock |
|---|---|---|
| 1mg | $96 | In-stock |
| 5mg | $420 | In-stock |
| 10mg | $630 | In-stock |
| 25mg | $1130 | In-stock |
| 50mg | $1700 | In-stock |
| 100mg | $2500 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-12828 |
| M.Wt: | 338.19 |
| Formula: | C15H13Cl2N3O2 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 50 mg/mL |
KH-CB19 is a potent CLK (cdc2-like kinase) inhibitor (CLK1 IC50=19.7 nM; CLK3 IC50=530 nM). KH-CB19 shows antiviral activity and inhibits influenza virus replication (IC50=13.6?μM)[1][2].
In Vitro: KH-CB19 (10 μM; 1 h) shows CLK inhibition on SR protein phosphorylation in human microvascular endothelial cells[1].
KH-CB19 (50?μM; 6 h) inhibits the disruption by CLK4 in A549?cells[2].
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