DBCO-NHS ester


CAS No. : 1353016-71-3

1353016-71-3
Price and Availability of CAS No. : 1353016-71-3
Size Price Stock
50mg $20 In-stock
100mg $27 In-stock
250mg $52 In-stock
1g $158 In-stock
5g $528 In-stock
10g $845 In-stock
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Cat. No. : HY-42973
M.Wt: 402.40
Formula: C23H18N2O5
Purity: >98 %
Solubility: DMSO : 50 mg/mL (ultrasonic)
Introduction of 1353016-71-3 :

DBCO-NHS ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. In Vitro:ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

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