BACE1-IN-2


CAS No. : 1352416-78-4

1352416-78-4
Price and Availability of CAS No. : 1352416-78-4
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Cat. No. : HY-112444
M.Wt: 421.35
Formula: C19H15F4N5O2
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 1352416-78-4 :

BACE1-IN-2 is a 1,4-Oxazine β-Secretase 1 (BACE1) inhibitor with an IC50 of 22 nM[1]. IC50 & Target:IC50: 22 nM (BACE1)[1] In Vitro:BACE1-IN-2 (Compound 3) is 10-fold more potent toward BACE1 than BACE2, inhibition of which may lead to hair depigmentation. BACE1-IN-2 inhibits hAβ42 cell with an IC50 of 6.0 nM[1].

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