CGS-12066 (maleate)
CAS No. : 1350965-83-1
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| 25mg | $327 | Get quote |
| 50mg | $517 | Get quote |
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| Cat. No. : | HY-123704 |
| M.Wt: | 450.41 |
| Formula: | C21H21F3N4O4 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
CGS-12066 (maleate) is a 5-HT receptor agonist. CGS-12066 has agonist effect for 5-HT1A , 5-HT1B ,5-HT1C and 5-HT1D with pEC50 values of 6.41, 7.56, 4.05 and 7.11, respectively. CGS-12066 can be used for the research of neurological disease[1].
IC50 & Target:pEC50: 6.41 (5-HT1A), 7.56 (5-HT1B), 4.05 (5-HT1C) and 7.11 (5-HT1D)[1].
pKD: 7.19 (5-HT1A), 6.94 (5-HT1B), 4.89 (5-HT1C) and 7.49 (5-HT1D)[1].
In Vitro:CGS-12066 (maleate) has agonist effect for 5-HT1A, 5-HT1B,5-HT1C and 5-HT1D with pEC50 values of 6.41, 7.56, 4.05 and 7.11, respectively[1].
CGS-12066 (maleate) has agonist effect for 5-HT1A, 5-HT1B,5-HT1C and 5-HT1D with pKD values of 7.19, 6.94, 4.89 and 7.49, respectively[1].
CGS-12066 (maleate) stimulates accumulation of inositol phosphates with low potency[1].
CGS-12066 (maleate) acts as partial agonist in inhibiting forskolin-stimulated adenylate cyclase activity in calf substantia nigra[1].
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