PI3K-IN-1
CAS No. : 1349796-36-6
(Synonyms: XL-147 derivative 1)
| Size | Price | Stock |
|---|---|---|
| 2mg | $55 | In-stock |
| 5mg | $88 | In-stock |
| 10mg | $154 | In-stock |
| 25mg | $308 | In-stock |
| 50mg | $440 | In-stock |
| 100mg | $715 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-12068 |
| M.Wt: | 599.66 |
| Formula: | C31H29N5O6S |
| Purity: | >98 % |
| Solubility: | DMSO : 27.5 mg/mL (ultrasonic;warming) |
PI3K-IN-1 (XL-147 derivative 1) is a potent inhibitor of PI3K. PI3K-IN-1 (25 μM) blocks PI3K/Akt signaling pathways[1]. In Vitro: PI3K-IN-1 (25 μM) blocks PI3K/Akt signaling pathways. By using the PI3K inhibitor PI3K-IN-1, TGF-β1 induced transformation into myofibroblast is also inhibited, with relatively reduced expressions of α-SMA, Col-1 and Timp-1[1].
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