| Size | Price | Stock |
|---|---|---|
| 5mg | $150 | In-stock |
| 10mg | $240 | In-stock |
| 25mg | $450 | In-stock |
| 50mg | $750 | In-stock |
| 100mg | $1200 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-117286 |
| M.Wt: | 540.12 |
| Formula: | C27H34ClN7OS |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 85 mg/mL |
(S)-JQ-35 (TEN-010) is an orally active, blood-brain barrier-permeable bromodomain inhibitor that selectively targets the bromodomain and extra-terminal domain (BET) protein family (BRD4, BRD3, BRD2 and BRDT). (S)-JQ-35 blocks the activation of Myc gene expression by BRD4, thereby inhibiting cancer cell proliferation and promoting cancer cell apoptosis. (S)-JQ-35 can be used in research related to NUT midline carcinoma and neuroblastoma[1][2]. In Vitro:(S)-JQ-35 (72 h) inhibits the viability of 15 neuroblastoma cell lines, with IC50 values ranging from 85 nM to 4.8 μM[2].
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