8-M-PDOT
CAS No. : 134865-70-6
(Synonyms: AH-002)
| Size | Price | Stock |
|---|---|---|
| 5mg | $80 | In-stock |
| 10mg | $145 | In-stock |
| 25mg | $342 | In-stock |
| 50mg | $600 | In-stock |
| 100mg | $1000 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-101358 |
| M.Wt: | 233.31 |
| Formula: | C14H19NO2 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
8-M-PDOT (AH-002) is a selective melatonin MT2 receptor agonist. 8-M-PDOT is 5.2-fold selective for MT2 over MT1 receptors. 8-M-PDOT binds human recombinant MT2 and MT2 receptors with pKi values of 8.23 and 8.95 respectively. 8-M-PDOT has anxiolytic-like activity[1][2]. IC50 & Target: pKi: 8.23 (Melatonin MT2 receptor) and 8.95 (Melatonin MT1 receptor)[2] In Vivo: 8-M-PDOT (10 µg/µL; administrated into the dorsal striatum by bilateral cannulas; for 30 minutes; male Wistar rats) treatment shows anxiolytic-like effect[2].
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