GE 2270A
CAS No. : 134861-34-0
(Synonyms: MDL 62879)
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| Cat. No. : | HY-106882 |
| M.Wt: | 1290.52 |
| Formula: | C56H55N15O10S6 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
GE 2270A (MDL 62879) is an antibiotic. GE 2270A inhibits gram-positive bacteria and anaerobes by inhibiting protein synthesis. GE 2270A can be used for the research of infection[1][2]. IC50 & Target:IC50: 0.4 μM (poly(U)-directed poly(Phe) synthesis)[2] In Vitro:GE 2270A (0.01-100 mg/L) inhibits poly(U)-directed poly(Phe) synthesis in cell-free systems with an IC50 value of 0.12 mg/L[1]. GE 2270A (0-0.1 mM; 10 min) is a strong inhibitor of protein biosynthesis in vitro as determined in a minimal E. coli purified system for poly(U)-directed poly(Phe) synthesis with an IC50 value of 0.4 μM[2].
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