COX-2-IN-2
CAS No. : 134729-13-8
| Size | Price | Stock |
|---|---|---|
| 1mg | $212 | In-stock |
| 5mg | $530 | In-stock |
| 10mg | $850 | In-stock |
| 25mg | $1700 | In-stock |
| 50mg | $2700 | In-stock |
| 100mg | $3645 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-101655 |
| M.Wt: | 341.36 |
| Formula: | C17H12FN3O2S |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
COX-2-IN-2 is a selective and inducible COX2 inhibitor with an IC50 of 0.24 μM. COX-2-IN-1 is an anti-inflammatory compound with anti-inflammatory and analgesic activities. IC50 & Target:IC50: 0.24 μM (COX2)[1] In Vitro:COX-2-IN-2 (Compound 19a) shows no COX-1 inhibition even at 100μM[1]. In Vivo:COX-2-IN-2 has oral ED50 values of 0.030 and 0.47mg/kg on adjuvant-induced arthritis and collagen-induced arthritis, respectively, and an ED30 value of 7.4mg/kg in the yeast-induced hyperalgesia (Randall-Selitto) assay. COX-2-IN-2 shows good analgesic activity and no ulcerogenicity[1].
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- HY-101655
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