Hydroxocobalamin
CAS No. : 13422-51-0
(Synonyms: Vitamin B12a)
| Size | Price | Stock |
|---|---|---|
| 5mg | $70 | In-stock |
| 10mg | $120 | In-stock |
| 25mg | $216 | In-stock |
| 50mg | $350 | In-stock |
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| Cat. No. : | HY-B2209 |
| M.Wt: | 1346.36 |
| Formula: | C62H89CoN13O15P |
| Purity: | >98 % |
| Solubility: | DMSO : 25 mg/mL (ultrasonic) |
Hydroxocobalamin (Vitamin B12a) is a cyanide antidote. Hydroxocobalamin can decrease the cell and plasma cyanide concentrations and increase survival rate in acute cyanide poisoning. Hydroxocobalamin can improve newborn Cbl-C defect-induced metabolic profile and neurocognitive outcome. Hydroxocobalamin can normalize Vitamin B12 deficiency. Hydroxocobalamin can induce acute kidney injury. Hydroxocobalamin can be used for the researches of metabolic and neurological disease[1][2][3][4][5][6].
In Vitro:Hydroxocobalamin (1 mM, 5 mins) recovers sodium cyanide-induced inotropy decrease in cardiac papillary muscle[1].
Hydroxocobalamin (500 μM, 10 mins) decreases intracellular cyanide in fibroblasts[1].
In Vivo:Hydroxocobalamin (150 mg/kg, i.v.) maintains higher systolic blood pressure in both controlled and uncontrolled hemorrhage swine models[2].
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