KF-14124
CAS No. : 134186-26-8
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| Cat. No. : | HY-117618 |
| M.Wt: | 409.50 |
| Formula: | C19H27N3O5S |
| Purity: | >98 % |
| Solubility: |
KF-14124, an orally active organic nitrate, a long-acting vasodilator with highly selective venous dilating action. KF-14124 is used in the study for angina pectoris. KF-14124 shows good oral inhibition of lysine-vasopressin induced coronary vasospasm with a potency[1][2]. In Vivo:KF-14124 (0.3 mg/kg intraduodenal administration (i.d.)) tends to decrease left ventricular end-diastolic pressure (LVEDP) in a Propranolol-induced heart failure model (dogs) and shows a potent protective effect against reperfusion arrhythmia in rats[1].
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