Dubermatinib
CAS No. : 1341200-45-0
(Synonyms: TP-0903)
| Size | Price | Stock |
|---|---|---|
| 1mg | $36 | In-stock |
| 5mg | $70 | In-stock |
| 10mg | $102 | In-stock |
| 25mg | $177 | In-stock |
| 50mg | $280 | In-stock |
| 100mg | $440 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-12963 |
| M.Wt: | 516.06 |
| Formula: | C24H30ClN7O2S |
| Purity: | >98 % |
| Solubility: | DMSO : 2 mg/mL (ultrasonic;warming;heat to 60°C) |
Dubermatinib (TP-0903) is a potent and selective Axl receptor tyrosine kinase inhibitor with an IC50 value of 27 nM. IC50 & Target:IC50: 27nM (Axl)[1] In Vitro:Dubermatinib (TP-0903) displays a potent activity against AXL with an IC50 of 0.027 μM. Dubermatinib (TP-0903) shows extremely potent activity in cell viability assays with an IC50 of 6 nM against the pancreatic cancer cell line PSN-1. Dubermatinib (TP-0903) is evaluated for its ability to block GAS6-mediated activation of AXL in pancreatic cancer cells. PSN-1 cells are serum-starved and then stimulated with GAS6 in the presence of various concentrations of TP-0903[1].
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- Dubermatinib
- Cat. No.:
- HY-12963
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