5-Methyltetrahydrofolic acid


CAS No. : 134-35-0

(Synonyms: 5-Methyl THF; 5-MTHF)

134-35-0
Price and Availability of CAS No. : 134-35-0
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50mg $50 In-stock
100mg $80 In-stock
500mg $200 In-stock
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Cat. No. : HY-113046
M.Wt: 459.46
Formula: C20H25N7O6
Purity: >98 %
Solubility: DMSO : 83.33 mg/mL (ultrasonic)
Introduction of 134-35-0 :

5-Methyltetrahydrofolic acid (5-Methyl THF) is the main circulating form of folic acid in the body and is involved in a variety of biochemical reactions. 5-Methyltetrahydrofolic acid regulates cardiovascular function by increasing the production of endothelin-1 (ET-1) in low-density lipoprotein-treated endothelial cells and can be used in the study of cardiovascular diseases[1][2]. In Vitro: 5-Methyltetrahydrofolic acid (0, 10, 50 and 100 μM; 24 h) increases the production of ET-1 in endothelial cells in a concentration-dependent manner[2].
5-Methyltetrahydrofolic acid (100 μM; 24 h) inhibits the production of thiobarbituric acid reactive substances (TBARS) by HUVEC in the presence of low-density lipoprotein[2].

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