Pelargonidin (chloride)


CAS No. : 134-04-3

134-04-3
Price and Availability of CAS No. : 134-04-3
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1mg $100 In-stock
5mg $195 In-stock
10mg $330 In-stock
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Cat. No. : HY-W011370
M.Wt: 306.70
Formula: C15H11ClO5
Purity: >98 %
Solubility: DMSO : 50 mg/mL (ultrasonic)
Introduction of 134-04-3 :

Pelargonidin chloride is an anthocyanidin and also is a scavenger of nitric oxide radical and has antioxidant activities. Pelargonidin inhibits cell viability and induces cell cycle arrest at sub-G1 phase. Pelargonidin chloride increases the mRNA and protein expression of HO-1, NQO1, Nrf2. Pelargonidin chloride improves Aβ-induced memory and learning impairment[1][2][3]. In Vitro:Pelargonidin chloride (10-100 µM; 1, 3, 5 days) inhibits cell viability in a time- and dose-dependent manner in JB6 P+ cells[2].
Pelargonidin chloride (10, 30, 50 µM; 3 days) induces cell cycle arrest at sub-G1 phase in a dose-dependent manner[2].
Pelargonidin chloride (0,10, 30, 50 µM; 5 days) increases the mRNA and protein expression of HO-1, NQO1, Nrf2 in a dose-dependent manner[2]. In Vivo:Pelargonidin (3 mg/kg; ip; once) chloride improves Aβ-induced memory and learning impairment in Morris water maze (MWM), increases the antioxidant power of hippocampus homogenate[3].

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