Ocifisertib (hydrochloride)
CAS No. : 1338799-83-9
(Synonyms: CFI-400945 (hydrochloride))
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| Cat. No. : | HY-12300A |
| M.Wt: | 571.11 |
| Formula: | C33H35ClN4O3 |
| Purity: | >98 % |
| Solubility: |
Ocifisertib hydrochloride (CFI-400945 hydrochloride) is the hydrochloride salt form of Ocifisertib (HY-12300). Ocifisertib hydrochloride is an orally active PLK4 inhibitor with a Ki and an IC50 of 0.26 nM and 2.8 nM. Ocifisertib hydrochloride inhibits growth of various cancer cells, arrests cell cycles at G2/M phase, and induces apoptosis. Ocifisertib hydrochloride exhibits antitumor efficacy in mouse model[1][2].
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- Ocifisertib (hydrochloride)
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