Epoxiconazole
CAS No. : 133855-98-8
| Size | Price | Stock |
|---|---|---|
| 5mg | $32 | In-stock |
| 10mg | $50 | In-stock |
| 25mg | $90 | In-stock |
| 50mg | $130 | In-stock |
| 100mg | $190 | In-stock |
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| Cat. No. : | HY-119683 |
| M.Wt: | 329.76 |
| Formula: | C17H13ClFN3O |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Epoxiconazole, a fungicide, is a demethylation inhibitor of the Ergosterol biosynthesis pathway. Epoxiconazole exhibits strong inhibitory effects on both carbendazim-resistant and phenamacril-resistant isolates, and can be used for controlling many crop diseases[1].
In Vitro:Epoxiconazole (150-300 g a.i./ha) inhibits mycelial growth and spore germination of wheat fusarium, increases the deoxynivalenol production and Tri5 gene expression[1].
Epoxiconazole (50 μM, 24 h) inhibits the cell viability of rat F98 glioma cell, causes cell morphological changes, apoptosis induction, cell cycle arrest (at G2/M phase), reactive oxygen species (ROS) generation, lipid peroxidation, DNA damage and cytoskeletal damage[2].
In Vivo:Epoxiconazole (0.08 mg/kg, po, once daily for 6 weeks) causes liver damage and induces oxidative stress in mouse liver. Epoxiconazole disturbs the intestinal flora, thereby causing damage to the intestinal barrier function in ICR mice[3].
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