GSK2606414


CAS No. : 1337531-36-8

1337531-36-8
Price and Availability of CAS No. : 1337531-36-8
Size Price Stock
5mg $119 In-stock
10mg $156 In-stock
25mg $280 In-stock
50mg $420 In-stock
100mg $648 In-stock
250mg $1040 In-stock
500mg $1407 In-stock
1g $1900 In-stock
5 g Get quote
10 g Get quote
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Cat. No. : HY-18072
M.Wt: 451.44
Formula: C24H20F3N5O
Purity: >98 %
Solubility: DMSO : ≥ 100 mg/mL
Introduction of 1337531-36-8 :

GSK2606414 is a cell-permeable and orally available protein kinase R-like endoplasmic reticulum (ER) kinase (PERK) inhibitor with an IC50 of 0.4 nM. IC50 & Target: IC50: 0.4 nM (PERK) In Vitro: GSK2606414 inhibits PERK activation in cells[1]. In Vivo: GSK2606414 (50 and 150 mg/kg, p.o.) inhibits the growth of a human tumor xenograft in mice[1].

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