AG 555
CAS No. : 133550-34-2
(Synonyms: Tyrphostin AG 555)
| Size | Price | Stock |
|---|---|---|
| 5mg | $50 | In-stock |
| 10mg | $80 | In-stock |
| 25mg | $140 | In-stock |
| 50mg | $210 | In-stock |
| 100mg | $315 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-15336 |
| M.Wt: | 322.36 |
| Formula: | C19H18N2O3 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL |
AG 555 (Tyrphostin AG 555), a potent antiretroviral drug, is a potent and selective inhibitor of EGFR and blocks Cdk2 activation[1][2].
IC50 & Target: EGFR[1]
In Vitro: AG 555 (100 μM) inhibits both the early stages (integration process) and the late stages (viral protein synthesis) in the virus life cycle[1].
Tyrphostins AG555, which blocks Cdk2 activation, induces growth arrest of immortalized cells at G1-S and early S and is very effective in arresting the growth of EGFR overexpressor cells[2].
Tyrphostin AG 555 can selectively suppress BPV-1 transcription through MAP kinase pathway activation and binding of phosphorylated Jun/ATF-2 at a novel intragenic regulatory sequence[3].
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